Help support your pet's liver via multiple pathways with one simple tablet. This product, #1 veterinarian- recommended, contains two powerful ingredients to help protect and support liver function, SAM-e (S-Adenosylmethionine) and Silybin, giving your pet benefits of both at once.
When liver function is compromised, the exact cause can often be difficult to determine. Supporting the liver, regardless of the cause, is essential to keep it working properly. Administering SAM-e (S-Adenosylmethionine), which is found in Denamarin, has been shown to markedly increase liver levels of glutathione, an important compound for liver health formed when SAM-e is metabolized. The SAM-e in Denamarin has also been shown to help protect liver cells from cell death and may help cell repair and regeneration.
Denamarin also helps support your pet's liver through the administration of Silybin. Silybin is an active part of an extract from milk thistle, known as silymarin, and has been shown to support liver function by helping maintain a healthy oxidative balance, helping to support the immune system.
While best known for supporting the liver in dogs and cats, Denamarin also has a place in supporting brain health. Research is looking into dog aging and associated decreases in levels of S-Adenosylmethionine (SAM-e) in cerebrospinal fluid, which surrounds the brain. Denamarin provides SAM-e in a stabilized form to help with brain health and act as a neuroprotector. Denamarin also provides a bioavailable form of Silybin, which supports oxidative balance, thus supporting the immune system. Enteric-coated tablets for dogs over 35 lbs.
Each tablet has 425 mg of S-Adenomethionine and 35 mg of Silybin A+B.
Shop all dog liver support.
For optimal absorption, tablets should be given on an empty stomach, at least one hour before feeding, as the presence of food decreases the absorption of S-Adenosylmethionine. For those owners who have difficulty administering tablets to their pets, Denamarin tablet(s) may be disguised in a small bit of food. It is recommended for pet owners to administer 3-6 cc of water immediately following any tablet administration to speed passage of the tablet into the stomach.
If the pet is to receive more than one tablet daily, the total number of tablets may be divided between morning and evening for ease of administration. For example, a daily administration of three tablets could be divided into two tablets in the morning and one tablet in the evening.
Denamarin can be used in conjunction with Marin® to provide additional Silybin levels and the benefits of Vitamin E and zinc supplementation. If Marin is used in conjunction with Denamarin, the two products should be administered 12 hours apart for best response.
||Number of Tablets
|Over 120 lbs
||Over 54.5 kg
*The number of tablets can be gradually reduced or increased at any time depending on the pet's needs. Many pets are maintained long-term on every-other-day or every third-day administration.
Storage: Store in a cool dry place not to exceed 86° F. Keep tablets in original blister pack until used. Tablets are sensitive to moisture and extreme heat.