For support of healthy liver function in dogs and cats
Recommended to help keep healthy levels of liver gluthathione, a potent antioxidant nutrient
Provides additional liver support to pets taking certain prescription arthritis medications long term
Supports healthy levels of glutathione, a powerful antioxidant and the liver's first line of defense. Use in dogs and cats to help support and maintain healthy liver function. Ideal for aging pets and for providing additional liver support to pets taking NSAIDs for arthritis management.
Contains S-Adenosylmethionine, which is recommended to increase levels of liver glutathione in dogs and cats. Glutathione is a potent antioxidant in support of liver health. Regular Tablets are packaged in foil blister packs to avert deterioration. Chewable Tablets are made for increased palatability, absorbed more quickly, and scored for easy portioning. 30 tablets per pack.
Suggested Daily Use: Given on empty stomach at least 1 hour before meal, preferably in the morning.
FOR CATS (Item 16316)
90 mg Denosyl
Up to 12
Up to 5.5
One Tablet Twice Daily
FOR SMALL DOGS (Item 16316)
90 mg Denosyl
Up to 12
Up to 5.5
FOR MEDIUM DOGS (Items 16317 & 70695)
225 mg Denosyl
13 to 34
6 to 15.5
FOR LARGE DOGS (Item 33878)
425 mg Denosyl
35 to 65
16 to 29.5
66 to 120
30 to 54.5
Active Ingredient: S-Adenosylmethionine
Denosyl, a nutritional supplement, is the pure and stabilized salt of S-Adenosylmethionin. It is the only brand researched in medical trials for veterinary use in dogs and cats.
S-Adenosylmethionine is an endogenous molecule synthesized by cells throughout the body and is formed from the amino acid methionine and ATP. It is an essential part of three major chemical pathways in the body.
Denosyl has been shown to increase hepatic glutathione levels in cats and dogs. Glutathione is a potent antioxidants that protects hepatic (liver) cells from toxins. A study found that low liver glutathione concentrations are common in dog and cats with decreased liver function.
For optimal absorption, tablets should be given on an empty stomach, at least 1 hour before feeding, as the presence of food decreases the absorption of S-Adenosylmethionine. For those owners who have difficulties administering tablets to their pets, this medication maybe disguised in a small bite of food. Studies have shown that, in many cases, tablets or capsules given as a "dry swallow" do not pass into the stomach in cats, but may become lodged in the esophagus. It is recommended for pet owners to administer 3-6 cc of water immediately following any tablet administration to speed passage of the tablet into the stomach. Denosyl 90- mg tablets are ideal for cats because of their small size.
Storage: Store in a cool, dry place. Keep tablets in original blister pack until used. Tablets are sensitive to moisture and extreme heat and should not be split or crumbled.
What does the liver do?
The liver participates in many activities within the body. It helps the digestion of food through production of bile and helps change digested foods into substances used by the body for energy and growth. The liver also helps process some medications into material(s) that can be used by the body; the liver may assist in eliminating medications from the body once they have had their effect. The liver stores vitamins and minerals and works with sugar (carbohydrates, glucose), fats and proteins. It also helps maintain proper blood clotting and removes many body toxins from the blood. Without proper liver function, the pet's health is compromised.
Because it does so much, the liver may be subject to many things: injury, both direct and indirect, infection, and toxicity. Some of the signs and symptoms of compromised liver function in pets may include: weakness, vomiting, poor appetite, and/or seizures. But if there is mild or early stage liver compromise, the pet can appear normal. If you notice any of these symptoms or your pet is just acting differently, you should contact your veterinarian. Many veterinarians run screening tests for middle aged and older patients during the annual examination to ensure that organ function is normal.
FREE economy ground shipping to 48 connecting states only on orders $19 or more. FREE economy ground shipping - NO MINIMUM - on any order containing Prescription or Flea and Tick products. See
full shipping rates here.