| Dosage Instructions
Ivomec Injection: Give subcutaneously only, to reduce risk of potentially fatal clostridial infection of the injection site. Animals should be appropriately restrained to achieve the proper route of administration. Use of a 16-gauge 1/2" to 3/4" needle is suggested. Inject under the loose skin in front of or behind the shoulder.
Injectable Ivermectin
Ivermectin is derived from the avermectins, a family of potent, broad-spectrum antiparasitic agents isolated from fermentation of Streptomyces avermitilis.
Ivermectin Injection is a clear, ready-to-use, sterile solution containing 1% ivermectin, 40% glycerol formal, 1.5% benzyl alcohol (preservative), and propylene glycol, q.s. ad 100%. It is formulated to deliver the recommended dose level of 200 mcg ivermectin/kilogram of body weight in cattle when given subcutaneously at the rate of 1 mL/110 lbs (50 kg).
In swine, ivermectin Injection is formulated to deliver the recommended dose level of 300 mcg ivermectin/kilogram body weight when given subcutaneously in the neck at the rate of 1 mL/75 lbs (33 kg.)
Dosage
Cattle: Ivermectin should be given only by subcutaneous injection under the loose skin in front of or behind the shoulder at the recommended dose level of 200 mcg ivermectin per kilogram of body weight. Each ml of ivermectin contains 10 mg of ivermectin, sufficient to treat 110 lbs (50 kg) of body weight (maximum 10 ml per injection site).
Body Weight (lbs) |
Dose (ml) |
| 220 |
2 |
| 330 |
3 |
| 440 |
4 |
| 550 |
5 |
| 660 |
6 |
| 770 |
7 |
| 880 |
8 |
| 990 |
9 |
| 1100 |
10 |
Swine: Ivermectin should be given only by subcutaneous injection in the neck of swine at the recommended dose level of 300 mcg of ivermectin per kilogram (2.2 lbs) of body weight. Each ml of ivermectin contains 10 mg of ivermectin, sufficient to treat 75 lbs of body weight.
| Growing Pigs |
Body Weight (lbs) |
Dose (ml) |
| 19 |
1/4 |
| 38 |
1/2 |
| 75 |
1 |
| 150 |
2 |
Breeding Animals (Sows, Gilts, and Boars) |
Body Weight (lbs) |
Dose (ml) |
| 225 |
3 |
| 300 |
4 |
| 375 |
5 |
| 450 |
6 |
Administration
Product Indications
Cattle: Ivermectin Injection is indicated for the effective treatment and control of the following harmful species of gastrointestinal roundworms, lungworms, grubs, sucking lice and mange mites in cattle:
Gastrointestinal Roundworms (adults and fourth-stage larvae):
Ostertagia ostertagi (including inhibited O. ostertagi), O. lyrata, Haemonchus placei, Trichostrongylus axei, T. colubriformis, Cooperia oncophora, C. punctata, C. pectinata, Oesophagostomum radiatum, Bunostomum phlebotomum, Nematodirus helvetianus (adults only), N. spathiger (adults only).
Lungworms (adults and fourth-stage larvae): Dictyocaulus viviparus
Cattle grubs (parasitic stages):
Hypoderma bovis, H. lineatum
Sucking Lice:
Linognathus vituli, Haematopinus eurysternus, Solenopotes capillatus
Mites (Scabies):
Psoroptes ovis (syn. P. communis var. bovis), Sarcoptes scabiei var. bovis
Persistent Activity
Ivermectin Injection has been proved to effectively control infections and to protect cattle from reinfection with Dictyocaulus viviparus for 28 days after treatment; Ostertagia ostertagi for 21 days after treatment; Oesophagostomum radiatum, Haemonchus placei, Trichostrongylus axei, Cooperia punctata, and Cooperia oncophora for 14 days after treatment.
Swine: Ivermectin Injection is indicated for the effective treatment and control of the following harmful species of gastrointestinal roundworms, lungworms, lice and mange mites in swine:
Gastrointestinal Roundworms (adults and fourth-stage larvae):
Large roundworm, Ascaris suum; Red stomach worm, Hyostrongylus rubidus; Nodular worm, Oesophagostomum spp.; Threadworm, Strongyloides ransomi (adults only).
Somatic Roundworm Larvae:
Threadworm, Strongyloides ransomi (somatic larvae)
Sows must be treated at least seven days before farrowing to prevent infection in piglets.
Lungworms:
Metastrongylus spp. (adults)
Lice:
Haematopinus suis
Mange Mites:
Sarcoptes scabiei var. suis
Swine: Ivermectin Injection is to be given subcutaneously in the neck. Animals should be appropriately restrained to achieve the proper route of administration. Use of a 16- or 18-gauge needle is suggested for sows and boars, while an 18- or 20-gauge needle may be appropriate for young animals. Inject under the skin, immediately behind the ear. Any single-dose syringe or standard automatic syringe equipment may be used with the 50 ml package size. As with any injection, sterile equipment should be used. The injection site should be cleaned and disinfected with alcohol before injection. The rubber stopper should also be disinfected with alcohol to prevent contamination of the contents. Mild and transient pain reactions may be seen in some swine following subcutaneous administration.
SWINE Recommended Treatment Program
At the time of initiating any parasite control program, it is important to treat all breeding animals in the herd. After the initial treatment, use ivermectin Injection regularly as follows:
BREEDING ANIMALS:
Sows: Treat prior to farrowing, preferably 7-14 days before, to minimize infection of piglets.
Gilts: Treat 7-14 days prior to breeding. Treat 7-14 days prior to farrowing.
Boars: Frequency and need for treatments are dependent upon exposure. Treat at least two times a year.
FEEDER PIGS
(Weaners/Growers/Finishers)
All weaner/feeder pigs should be treated before placement in clean quarters.
Pigs exposed to contaminated soil or pasture may need retreatment if reinfection occurs.
NOTE: (1) Ivermectin Injection has a persistent drug level sufficient to control mite infestations throughout the egg to adult life cycle. However, since the ivermectin effect is not immediate, care must be taken to prevent reinfestation from exposure to untreated animals or contaminated facilities. Generally, pigs should not be moved to clean quarters or exposed to uninfested pigs for approximately one week after treatment. Sows should be treated at least one week before farrowing to minimize transfer of mites to newborn baby pigs.
(2) Louse eggs are unaffected by Ivermectin Injection and may require up to three weeks to hatch. Louse infestations developing from hatching eggs may require retreatment.
(3) Consult a veterinarian for aid in the diagnosis and control of internal and external parasites of swine.
Ivermectin Injection for Cattle and Swine has been developed specifically for use in cattle, swine, reindeer, and American bison only. This product should not be used in other animal species as severe adverse reactions, including fatalities in dogs, may result.
Protect product from light.
When to Treat Cattle with Grubs
Ivermectin effectively controls all stages of cattle grubs. However, proper timing of treatment is important. For most effective results, cattle should be treated as soon as possible after the end of the heel fly (warble fly) season.
Destruction of Hypoderma larvae (cattle grubs) at the period when these grubs are in vital areas may cause undesirable host-parasite reactions including the possibility of fatalities. Killing Hypoderma lineatum when it is in the tissue surrounding the esophagus (gullet) may cause salivation and bloat: killing H. bovis when it is in the vertebral canal may cause staggering or paralysis. These reactions are not specific to treatment with ivermectin, but can occur with any successful treatment of grubs. Cattle should be treated either before or after these stages of grub development. Consult your veterinarian concerning the proper time for treatment.
Cattle treated with ivermectin after the end of the heel fly season may be retreated with ivermectin during the winter for internal parasites, mange mites, or sucking lice without danger of grub-related reactions. A planned parasite control program is recommended.
Store at room temperature away from light. Keep away from children and pets. |