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Brand Name
Clomicalm
Common Drug Name
Clomipramine
Pronunciation
kloe-MIP-ra-meen
What should I discuss with my veterinarian while considering Clomipramine?
Talk to your veterinarian, in detail, about the behavior modification techniques you should use in conjunction with Clomipramine. Have your veterinarian explain the other treatment options that may be available to treat your pet's condition.
Tell your veterinarian if your dog is a male and used for breeding or if your dog has had seizures.
Notify your veterinarian of any other medications or supplements your pet is receiving, especially selegiline (L-deprenyl, Anipryl), or amitraz (Preventic collars or Mitaban dip). Also tell your veterinarian if your pet has had any reactions to previous medications.
What should I do if I miss a dose?
If you miss a dose, give it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to the regular schedule. Do not give two doses at once.
What is the most important information I should know?
To be effective, Clomipramine needs to be used in conjunction with behavior modification methods that will help your pet change the unwanted behavior. Overdoses can be very toxic, so keep Clomipramine out of the reach of children and pets.
Who should not take it?
Not for use in animals hypersensitive (allergic) to Clomipramine or other tricyclic antidepressants, such as amitriptyline.
Use with caution in animals with epilepsy, seizures, urine retention (problems urinating), decreased stomach/intestinal motility, constipation, liver or kidney disease, heart rhythm disturbances, thyroid
disease, or glaucoma.
The safety of the drug has not been determined in pregnant, or lactating dogs and cats (female animals nursing their young). Do not use in males used for breeding.
Do not use in animals who are being treated, or have recently been treated with selegiline (L-deprenyl, Anipryl) or amitraz (Preventic collars or Mitaban dip).
What side effects may be seen when taking Clomipramine?
May see lack of appetite, vomiting, increased appetite and weight gain, diarrhea, lethargy, sleepiness, dry mouth, difficulty urinating, or increased heart rate. Contact your veterinarian if these side effects are severe or persistent.
If your pet experiences an allergic reaction to the medication, signs may include facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately.
How is it stored?
Store at room temperature in a tightly-closed container. Keep out of reach of children and pets.
What should I do if I know of or suspect there has been an overdose?
Should overdose occur, your pet may have life-threatening reactions, such as seizures, heart arrhythmias, and heart failure, which may result in weakness, collapse, rapid breathing, or pale gums.
If you know or suspect your pet has had an overdose, or if you observe any of these signs in your pet, contact your veterinarian immediately.
What should I avoid when giving my pet Clomipramine?
Consult your veterinarian before using Clomipramine with vitamins and supplements, monoamine oxidase inhibitors (MAOIs), such as selegiline (Anipryl), isoniazid, or amitraz (an ingredient in some tick collars, and in Mitaban, a treatment for mange), flea and tick collars, insulin, other antidepressant
drugs, other drugs with anticholinergic effects (such as atropine), methimazole, other antithyroid drugs, fluoxetine, ketoconazole, or itraconazole, or cimetidine, since interactions may occur. Clomipramine may alter blood glucose levels. Avoid giving aged cheese to pets receiving Clomipramine. Aged cheese contains a chemical that could increase adverse side effects, since that chemical and the drug act on the same enzyme system in the body.
Where is more information available?
Ask your veterinarian, consult with one of our pharmacists at 1-800-447-3021, or see the
Patient Information Sheet on this medication.
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