Common Drug Name
What should I discuss with my veterinarian while considering Trifexis?
Some intestinal parasites, such as hookworms and roundworms can be spread to people. Talk to your veterinarian about other measures you can take to prevent your pet from being infected with intestinal worms, and protecting yourself.
Notify your veterinarian of any other medications or supplements your pet is taking, and also if your pet has had any reactions to previous medications.
What should I do if I miss a dose?
If vomiting occurs within one hour of administration, redose with another full dose.
What is the most important information I should know?
Who should not take it?
Consult your veterinarian regarding heartworm testing your dog prior to and during use of this medication.
Use with caution in dogs with pre-existing epilepsy.
Not for use in Collies or other herding breeds over the recommended heartworm prevention dose unless under the strict supervision of a veterinarian. If your dog is one of these breeds and received a higher dose, observe your pet for at least 8 hours after giving the medication for weakness, staggering, fever, dilated pupils, trembling, or pressing the head against a wall. Contact your veterinarian immediately if you see these signs.
Do not use in puppies less than 8 weeks of age or less than 5 pounds.
Use with caution in breeding females. The safe use of milbemycin oxime plus spinosad in breeding males has not been evaluated.
Consult your veterinarian regarding physical examinations and heartworm testing your pet prior to, and during, treatment with Trifexis.
Properly dispose of unused medication, as it may be toxic to fish and other animals.
What side effects may be seen when taking TriFexis?
Since the introduction of Trifexis, additional side effects reported are trembling/shaking, ataxia, seizures, and hypersalivation.
If your pet experiences an allergic reaction to the medication or the dying of parasites, signs may include facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately.
How is it stored?
What should I do if I know of or suspect there has been an overdose?
If you know or suspect your pet has had an overdose, or if you observe any unusual signs, symptoms, or behaviors, contact your veterinarian immediately.
What should I avoid when giving my pet Trifexis?
Serious adverse reactions have been reported following the simultaneous use of spinosad and ivermectin at doses higher than the heartworm prevention dose.
No known food interactions.
Where is more information available?