Advantage ® II Topical Flea Treatment for Dogs

Advantage II takes superior flea control to the next level with the addition of the insect growth regulator (IGR) pyriproxyfen. New and improved Advantage II now actively targets the ENTIRE flea life cycle for effective treatment of existing fleas and prevention of flea infestation.

Advantage II still contains the proven active ingredient, imidacloprid, found in Advantage, which kills 98-100% of adult fleas within 12 hours, stops fleas from biting in 3-5 minutes, and kills re-infesting fleas within 2 hours. The result is fast-acting relief from biting adults whether your dog has fleas or picks up fleas from another animal.

The addition of the insect growth regulator (IGR) pyriproxyfen means Advantage II inhibits development of flea eggs and larvae to break the flea life cycle, so there is no development into biting, breeding adults. Advantage II is a non-prescription topical flea control treatment specializing in fast, convenient and economical flea control. Also an effective treatment against chewing lice on dogs.

Advantage II remains effective following a shampoo treatment, swimming, or after exposure to rain or sunlight. No-odor, easy-squeeze tube makes it easy to apply. One tube can be effective for up to one month. Each package contains pre-measured, childproof, easy-to-use squeeze tubes. For dogs only: 7 weeks or older. Do not use on cats.

Advantage II does not kill ticks.

When treating your dog with Advantage II, we recommend using Hypo-Allergenic Shampoo when bathing your dog.

Advantage® II is manufactured by Bayer, a trusted and dedicated name in animal healthcare. Available in 4 different weight ranges for dogs and puppies. Guaranteed USA Supplier.

Check out K9 Advantix II - Highly recommended by Dr. Foster and Dr. Smith and used on all their dogs! Looking for Advantage II for Cats?

Please click on "More Information" for Advantage II Indications and Usage directions.

Important Precautions
Hazards to humans: Advantage causes eye irritation. Harmful if swallowed. Do not get in eyes or on clothing. Avoid contact with skin. Wash hands thoroughly with soap and warm water after handling. Keep out of reach of children.

Hazards to domestic animals: Advantage is for external use only. Do not use on puppies under seven weeks of age. As with any product, consult your veterinarian before using this product on debilitated, aged, pregnant, or nursing animals. Individual sensitivities, while rare, may occur after using ANY pesticide product for pets. If signs persist, or become more severe, consult a veterinarian immediately. If your animal is on medication, consult your veterinarian before using this or any product.

How to Apply

1. Use only on dogs. Do not use on other animals.
2. Remove one applicator tube from the package.
3. Hold applicator tube in an upright position. Pull cap off tube.
4. Turn the cap around and place other end of cap back on tube.
5. Twist cap to break seal, then remove cap from tube.
6. Application
   • For Dogs 10 lbs and under & 11-20 lbs: The dog should be standing for easy application. Part the hair on the dog's back, between the shoulder blades, until the skin is visible. Place the tip of the tube on the skin and squeeze the tube to expel the entire contents directly on the skin. Do not get this product in your dog's eyes or mouth.
   • For Dogs 21-55 lbs & Over 55 lbs: The dog should be standing for easy application. The entire contents of the Advantage II tube should be applied evenly to three or four spots on the top of the back from the shoulder to the base of the tail. At each spot, part the hair until the skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of the solution at any one spot that could cause some of the solution to run off the side of the dog. Do not get this product in your pet's eyes or mouth.
7. Discard empty tube as described in Storage and Disposal.
8. In case of a severe flea infestation, retreatment may be necessary earlier than four weeks. Do not retreat more often than once every seven days. After flea control is attained, return to a monthly retreatment schedule.

Storage and Disposal
Do not contaminate water, food, or feed by storage or disposal. Storage: Store in a cool, dry place. Protect from freezing. Pesticide Disposal: securely wrap original container in several layers of newspaper and discard in trash. Container disposal: Do not reuse empty container. Wrap container and put in trash.

Not for use in cats.

What is the life cycle of fleas?

There are four stages in the development of fleas: eggs and adults. Male and female fleas mate and two days later the female flea starts laying eggs. The eggs are often laid on the animal, but because they are not sticky, fall off into the environment. Along with the eggs, the female flea deposits a large amount of feces (often called "flea dirt"). The flea dirt will dissolve into a red color when moistened; this is because it is primarily digested blood. The flea lays 30-50 eggs per day, generally in batches of 3 to 15. A flea can produce 400-1,000 eggs in her lifetime (several months to two years, depending on the species). Two days (or more depending on temperature) after the egg is laid it hatches and the larva, which looks like a tiny maggot, starts to feed on the feces left by its mother. The larva passes through several phases of development taking a total of about a week. At that time the larvae starts spinning a cocoon and is called a pupa. The cocoon is sticky and will often become covered with fine dirt or sand, and can be found deep in carpet or crevices. In a week, the pupa develops into an adult and emerges from the cocoon when it senses vibrations, carbon dioxide, or warmth, which tells it an animal host is near. The entire life cycle takes about 15 days, but the pupa can remain dormant under inhospitable conditions (e.g., cold) and extend the cycle to over a year. This is important to remember when planning flea control.