Revolution^® (Brand) by Pfizer

What is Revolution?
This once-a-month topical (on-the-skin) treatment is truly a revolutionary idea in parasite protection. In Cats, Revolution protects against heartworm, roundworms, hookworms, fleas, and even mites when used as directed. In Dogs, Revolution protects against heartworm, fleas, ticks, and even mites when used as directed.

Who is it for?
For dogs/puppies over 6 weeks of age and cats/kittens over 8 weeks of age. Safe to use on pregnant and nursing animals.

What are the benefits?

How does Revolution work?
Revolution is used in the prevention, control, and treatment of various parasite infections. The active ingredient is selamectin, which interferes with the parasite's nervous system. It is an effective heartworm preventive, killing the immature form of the heartworm (Dirofilaria immitis). It kills adult fleas (Ctenocephalides felis) and prevents flea eggs from hatching for one month. It is also used for the treatment and control of ear mites (Otodectes cynotis) and sarcoptic mange (Sarcoptes scabiei). Revolution is effective in controlling tick infestations due to the American dog tick (Dermacentor variabilis). In cats, Revolution also treats and controls roundworm and hookworm infections.

How is it given?
For the prevention of heartworm disease, Revolution must be applied monthly, preferably on the same date each month. Drs. Foster and Smith recommends (and our guarantee requires) that Revolution be used year round, although some veterinarians may recommend using it only during the mosquito season. If used seasonally, the first dose must be applied within 30 days of the pet's first exposure to mosquitoes. The last dose must be applied within 30 days after the pet's last exposure to mosquitoes.

To control fleas, apply the first dose one month prior to the expected start of the flea season.

Part the hair on the back of the pet at the base of the neck in front of the shoulder blades. Place the tip of the tube on the skin and squeeze the tube 3-4 times to empty the entire contents on the skin. Do not massage into skin or apply to broken skin. Do not apply when the haircoat is wet.

What results can I expect?
Revolution will kill the immature heartworms the pet was exposed to in the preceding month. For ear mites and sarcoptic mange, most mites are killed with one treatment, although a second treatment a month later may be required; follow the advice of your veterinarian. To control ticks, the dosage may need to be changed from the heartworm dose of once a month; again follow your veterinarian's recommendations. Most fleas are killed within 36 hours of application. If the pet was already infested with fleas when Revolution was applied, you may see fleas after that period of time as the immature forms of the fleas in the environment hatch.

What form(s) does it come in?
Topical

Please click on "More Information" for possible drug and food interactions with this medication.

Brand Name
Revolution

Pronunciation
REV-o-LOO-shun

Common Drug Name
Selamectin

What should I discuss with my veterinarian while considering Revolution?
Talk to your veterinarian about the heartworm testing that is recommended before starting your pet on a heartworm prevention program.

Collies or other herding breeds may have a reaction to selamectin if given over the recommended heartworm prevention dose. If your dog is one of these breeds, and your veterinarian has prescribed Revolution, observe your pet for at least 8 hours after giving the medication for weakness, staggering, dilated pupils, trembling, drooling, or pressing the head against a wall. Contact your veterinarian immediately if you see these signs.

Some intestinal parasites, such as hookworms and roundworms can be spread to people. Talk to your veterinarian about other measures you can take to prevent your pet from being infected with intestinal worms, and protecting yourself.

Notify your veterinarian of any other medications or supplements your pet is taking, and also if your pet has had any reactions to previous medications.

What should I do if I miss a dose?
If a dose is missed and over 30 days have gone by since the last dose, apply Revolution immediately and resume a monthly dosing schedule. Tell your veterinarian that a dose was missed.

What is the most important information I should know?
If the interval between doses is longer than one month, the efficacy of the drug is reduced. Do not give this medication orally.

Who should not take it?
Do not use on puppies less than 6 weeks of age or kittens less than 8 weeks of age. Use with caution in sick, weak, or underweight animals. Safe to use on breeding animals and pregnant and nursing females.

Collies and herding breeds may have a reaction to Revolution.

This medication should only be given to the pet for which it was prescribed.

What side effects may be seen when taking Revolution?
Side effects are very rare, but may include incoordination, trembling, or drooling. If Revolution is accidently given orally, you may see drooling and vomiting. Contact your veterinarian immediately if you observe any of these signs.

How is it stored?
Store below 86°F. Keep out of reach of children and pets.

What should I do if I know of or suspect there has been an overdose?
If you know or suspect your pet has had an overdose, or if you observe weakness, staggering, dilated pupils, trembling, drooling, or pressing the head against a wall, contact your veterinarian immediately.

What should I avoid when giving my pet Revolution?
Although there are no known drug or food interactions with this medication, consult with your veterinarian before using Revolution with any other medications, including vitamins and supplements, since interactions may occur.

Where is more information available?
Ask your veterinarian, consult with one of our pharmacists at 1-800-447-3021, or see the Patient Information Sheet on this medication. For technical assistance or to report suspected adverse reactions, call the manufacturer, Pfizer, at 1-800-366-5288.