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Brand Name
Reconcile™ is a veterinary product. Prozac is a human product.
Pronunciation
floo-OX-e-teen
Common Drug Name
Fluoxetine Hydrochloride
What should I discuss with my veterinarian while considering Fluoxetine?
Fluoxetine should be used in conjunction with techniques to try to change the unwanted behavior. Discuss, in detail, what behavior modification techniques will work on your pet. Also discuss how long the treatment period will be and what type of outcome is expected. You and your veterinarian should talk about any other treatment options that are recommended for your pet.
Tell your veterinarian if your pet has had seizures, has diabetes or liver disease, may be pregnant, is nursing, or if you intend to breed your pet.
Notify your veterinarian of any other medications or supplements your pet is taking, and also if your pet has had any reactions to previous medications, especially selegiline (Anipryl) or amitraz (Preventic tick collars or Mitaban).
What should I do if I miss a dose?
If you miss a dose, give it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to the regular schedule. Do not give two doses at once.
What is the most important information I should know?
To be most effective, Fluoxetine needs to be used in combination with behavior modification techniques.
Consult your veterinarian before using other medications or tick collars along with Fluoxetine.
Contact your veterinarian immediately if your pet would have a seizure while taking Fluoxetine.
Who should not take it?
Not for use in animals hypersensitive (allergic) to Fluoxetine, sertraline (Zoloft) or paroxetine (Paxil). The safety of using Fluoxetine in pregnant animals has not been determined. Use with caution in in lactating animals (female animals nursing their young), since the drug enters the breast milk. Do not use in animals with a history of epilepsy or seizures. Use with caution in animals with liver disease and in diabetic animals since Fluoxetine may alter blood sugar levels.
What side effects may be seen when taking Fluoxetine?
The most common side effect is loss of appetite, which is usually temporary. Try feeding your pet by hand, offering more flavorful foods, or, for dogs and cats, slightly warming canned foods. If your pet
is on a special diet because of a medical condition, consult your veterinarian before changing or adding other foods. Also consult your veterinarian if your pet's appetite does not return to normal.
May also see loss of appetite, weight loss, lethargy, vomiting, shaking, diarrhea, restlessness, excessive vocalization, anxiety, sleep disturbances, hyperactivity, behavior changes and irritability. In dogs may also see panting.
In cats may also see changes in elimination patterns (urinating and defecating). Consult your veterinarian if you notice any of the above side effects.
Fluoxetine may cause aggression in some dogs. If this occurs, contact your veterinarian immediately.
If your pet experiences an allergic reaction to the medication, signs may include facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately.
How is it stored?
Store at room temperature in a tight, light-resistant, childproof container. Do not remove the desiccant, if present. Keep out of reach of children and pets.
What should I do if I know of or suspect there has been an overdose?
Should overdose occur, you may see behavior changes, tremors, seizures, or liver disease, with vomiting.
If you know or suspect your pet has had an overdose, or if you observe any of these signs in your pet, contact your veterinarian immediately.
What should I avoid when giving my pet Fluoxetine?
Notify your veterinarian of any other medications, including vitamins and supplements, your pet is taking while your pet is receiving Fluoxetine. Do not use with ephedrine or monoamine oxidase inhibitors (MAOIs) such as isoniazid, selegiline (deprenyl, Anipryl) or amitraz (an ingredient in some tick collars, and in Mitaban, a treatment for mange). These products need to be discontinued for 2-5 weeks before Fluoxetine can be safely given. Consult your veterinarian before using other medications or tick collars along with Fluoxetine.
Consult your veterinarian before using Fluoxetine with warfarin, phenylbutazone, and digoxin, L-tryptophan, diazepam (Valium), buspirone, clomipramine (Clomicalm) and other tricyclic antidepressants (such as amitriptyline), or metoclopramide, since interactions may occur.
Where is more information available?
Ask your veterinarian, consult with one of our pharmacists at 1-800-447-3021, or see the Patient Information Sheet on this medication. | 
