Flea & Tick Products for Dogs Comparison Chart
Drs. Foster & Smith Educational Staff

Compare and Shop Flea & Tick

Compare! Bio Spot®
Defense
Spot On®
Advan-
tage® II
K9 Advan-
tix® II
Fipro-
guard™
Front-
line
Plus®
Pro-
gram®
Certifect
Kills Adult
Fleas
Yes Yes Yes Yes Yes No Yes
Controls
Flea
Develop-
ment
Yes Yes Yes No Yes Yes Yes
Kills Ticks
(Lyme Disease
vectors)
Yes No Yes Yes Yes No Yes
Repels &
Kills
Mosquitoes

(Heartworm,
West Nile
Virus
carriers)
Yes No Yes No No No No
Repels &
Kills
Biting
Flies
and/or
Lice
Yes No Yes Yes
(Lice)
Yes
(Lice)
No Yes
(Lice)
Admini-
stration
Apply
Topically

Apply
Topically

Apply
Topically

Apply
Topically

Apply
Topically

Oral
Pill

Apply
Topically
Dosage Monthly
Monthly
Monthly
Monthly
Monthly
Monthly
Monthly
Minimum
Age
For
Dogs
6 months
& older
For
Dogs
> 7 wks
For
Dogs
7 wks
& older
For
Dogs
8 wks
& older
For
Dogs
8 wks
& older
For
Dogs &
Cats
6 wks
& older
For
Dogs
8 wks
& older
& at least
5 lbs
Active
Ingre-
dients
Etofen-
prox,
S-meth-
oprene IGR
& Piper-
onyl
Butoxide
Imidac-
loprid &
Pyriproxy-
fen IGR
Perme-
thrin,
Imidac-
loprid &
Pyri-
proxyfen
IGR
Fipronil Fipronil
& Metho-
prene IGR
Lufen-
uron
Fipronil,
& Metho-
prene
& Amitraz

Additional charges for an office visit frequently apply if you purchase from your veterinarian.
Frontline Plus® is a registered trademarks of Merial.
Advantage® II is a registered trademark of the Bayer Corp.