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Pronunciation
TOO-coe-prim
Common Drug Name
Trimethoprim with sulfadiazine or TMP-SDZ.
What should I discuss with my veterinarian while considering Tucoprim?
Talk to your veterinarian about what tests and exams may be necessary while your horse is taking Tucoprim. Also discuss how long the treatment period will be and what type of outcome is expected.
Tell your veterinarian if your horse has liver or blood diseases, a blood clotting disorder, or may be pregnant or is nursing, or if you intend to breed your horse.
Notify your veterinarian of any other medications or supplements your horse is taking, and also if your horse has had any reactions to previous medications.
What should I do if I miss a dose?
If you miss a dose, give it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to the regular schedule. Do not give two doses at once.
What is the most important information I should know?
Tucoprim should be given exactly as your veterinarian directs. If a full treatment regimen is not finished, the infection could come back.
Always have plenty of drinking water available - your horse should not become dehydrated while taking Tucoprim
If you notice diarrhea or any change in manure, contact your veterinarian immediately.
Who should not take it?
Not for use in horses hypersensitive (allergic) to trimethoprim, sulfadiazine or other sulfa drugs. Do not use in horses with liver disease or blood diseases. The effects of trimethoprim/sulfa on pregnancy in horses has not been determined. Do not use in pregnant or lactating horses unless benefits outweigh the risks.
Do not use in horses intended for food.
What side effects may be seen when taking Tucoprim?
Sulfa crystals may be found in the horse's urine during a urinalysis (a test on the urine). This does not pose a problem in horses that remain well hydrated. In rare cases, horses can develop severe and even fatal diarrhea when given Tucoprim. If you notice diarrhea or any change in the manure, consult your
veterinarian immediately.
Other less common side effects include anemia resulting in pale gums and tiredness, and low platelets resulting in bleeding tendencies.
If your horse experiences an allergic reaction to the medication, signs may include facial swelling, hives, scratching, sudden onset of diarrhea, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately.
How is it stored?
Store at room temperature in a tight, light-resistant, childproof container. Keep out of the reach of children and pets.
What should I do if I know of or suspect there has been an overdose?
If an overdose has occurred, you may see signs of colic, diarrhea, depression, confusion, facial swelling,
anemia resulting in pale gums and tiredness, and bleeding tendencies. If you know or suspect your horse has had an overdose, or if you observe any of these signs in your horse, contact your veterinarian immediately.
What should I avoid when giving my pet Tucoprim?
Notify your veterinarian of any other medications, including vitamins and supplements, your horse is taking while receiving Tucoprim.
Consult your veterinarian before using Tucoprim with methotrexate, anticoagulants such as warfarin, phenylbutazone, thiazide diuretics, salicylates (aspirin), probenecid, cyclosporine, phenytoin, detomidine, xylazine,or romifidine (Sedivet), since interactions may occur.
Antacids may decrease the effectiveness of sulfa drugs like Tucoprim, so give the antacid 2-3 hours before or after a dose of the sulfa drug.
Where is more information available?
Ask your veterinarian, consult with one of our pharmacists at 1-800-447-3021, or see the Patient Information Sheet on this medication.
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